Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.49 |
| ▸ | PPARA | Q07869 | 16/20 | 0.49 |
| ▸ | PPARD | Q03181 | 14/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988751 | 0.96 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL5992535 | 0.91 | PPARD (0.58) | PPARGPPARAPPARD | |
| SCHEMBL5990307 | 0.85 | PPARA (0.58) | PPARGPPARAPPARD | |
| SCHEMBL5991190 | 0.84 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5992008 | 0.80 | PPARD (0.61) | PPARGPPARAPPARD | |
| SCHEMBL5989640 | 0.80 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL5991917 | 0.78 | PPARD (0.74) | PPARGPPARAPPARD | |
| SCHEMBL5990816 | 0.78 | PPARG (0.61) | PPARGPPARAPPARD | |
| SCHEMBL5989606 | 0.78 | KCNQ3 (0.44) | PPARGPPARAPPARD | |
| SCHEMBL5991207 | 0.75 | PPARG (0.60) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |