Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990267 | 1.00 | PPARG (0.41) | PPARGPPARDPPARATTRTNF | |
| SCHEMBL5991196 | 0.84 | PPARG (0.56) | PPARGPPARDPPARA | |
| SCHEMBL5990286 | 0.84 | PPARG (0.56) | PPARGPPARDPPARA | |
| SCHEMBL5990128 | 0.84 | PPARG (0.56) | PPARGPPARDPPARA | |
| SCHEMBL5990452 | 0.83 | PPARG (0.57) | PPARGPPARDPPARATTR | |
| SCHEMBL5990443 | 0.83 | PPARG (0.57) | PPARGPPARDPPARATTR | |
| SCHEMBL5990524 | 0.81 | PPARG (0.58) | PPARGPPARDPPARA | |
| SCHEMBL5990518 | 0.81 | PPARG (0.58) | PPARGPPARDPPARA | |
| SCHEMBL5989110 | 0.80 | PPARG (0.42) | PPARGPPARDPPARA | |
| SCHEMBL5989115 | 0.80 | PPARG (0.42) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |