Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.59 |
| ▸ | PPARG | P37231 | 10/20 | 0.59 |
| ▸ | PPARA | Q07869 | 10/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990488 | 1.00 | PPARD (0.59) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL5990567 | 0.92 | PPARD (0.56) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL5990571 | 0.92 | PPARD (0.56) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL5990514 | 0.90 | PPARD (0.60) | PPARDPPARGPPARA | |
| SCHEMBL5990508 | 0.90 | PPARD (0.60) | PPARDPPARGPPARA | |
| SCHEMBL5988781 | 0.87 | PPARG (0.67) | PPARDPPARGPPARA | |
| SCHEMBL5988776 | 0.87 | PPARG (0.67) | PPARDPPARGPPARA | |
| SCHEMBL5989374 | 0.84 | PPARD (0.55) | PPARDPPARGPPARA | |
| SCHEMBL5989365 | 0.84 | PPARD (0.55) | PPARDPPARGPPARA | |
| SCHEMBL5989235 | 0.84 | PPARD (0.56) | PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |