⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272181 | 0.77 | — | — | |
| SCHEMBL13351086 | 0.77 | — | — | |
| SCHEMBL8407787 | 0.74 | — | — | |
| SCHEMBL27756603 | 0.74 | — | — | |
| SCHEMBL3306417 | 0.74 | — | — | |
| SCHEMBL24295384 | 0.74 | — | — | |
| SCHEMBL8404911 | 0.74 | — | — | |
| SCHEMBL6903733 | 0.72 | — | — | |
| SCHEMBL3306935 | 0.70 | — | — | |
| SCHEMBL11211179 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39072-E1 | 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-18 | — | — | US | disclosed |
| EP-1319651-B1 | 2-Aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor | MITSUBISHI PHARMA CORP (JP) | 2005-06-29 | — | — | EP | disclosed |
| EP-1002792-B1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1319651-A2 | 2-Aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor | Mitsubishi Pharma Corporation (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6214873-B1 | PREVENTION OR SUPPRESION OF REJECTION OF ORGANS OR BONE MARROW TRANSPLANTATION; TREATMENT OF AUTOIMMUNE DISEASES OR ALLERGIC DISEASES; DECREASE IN TOXICITY AND HIGHER SAFETY | WELFIDE CORPORATION (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-1002792-A1 | 2-AMINOPROPANE-1,3-DIOL COMPOUNDS, MEDICINAL USE THEREOF, AND INTERMEDIATES IN SYNTHESIZING THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-0162217-A1 | 1,2,4-Triazacycloalcadiene derivatives | CIBA-GEIGY AG (CH) | 1985-11-27 | — | — | EP | disclosed |
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| EP-0061425-A2 | Thiazole derivatives, processes for their preparation, medicaments containing them and their use | CIBA-GEIGY AG (CH) | 1982-09-29 | — | — | EP | disclosed |
| US-4049561-A | EXTREME PRESSURE ADDITIVE SELECTED FROM A PARTIAL AMIDE OF A DI- OR TRI-CARBOXYLIC ACID, A THIOETHER, AND A HYDROCARBYL PHOSPHATE | CHEVRON RESEARCH COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-4049562-A | PARTIAL ALCOHOL ESTERS OF A DI- OR TRI-CARBOXYLIC ACID, THIOETHERS, HYDROCARBYL PHOSPHATES | CHEVRON RESEARCH COMPANY (US) | 1977-09-20 | — | — | US | disclosed |