Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 7/20 | 0.54 |
| ▸ | CA1 | P00915 | 7/20 | 0.54 |
| ▸ | CA2 | P00918 | 7/20 | 0.54 |
| ▸ | CA9 | Q16790 | 7/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RNF168 | Q8IYW5 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412852 | 0.80 | TDP1 (0.74) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL29897722 | 0.79 | CA12 (0.79) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL27075286 | 0.78 | TDP1 (0.72) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL6034966 | 0.77 | TDP1 (0.74) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL15280591 | 0.77 | TDP1 (0.74) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL17208802 | 0.77 | TDP1 (0.74) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL17128734 | 0.77 | TDP1 (0.67) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL17933958 | 0.77 | TDP1 (0.74) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL15986928 | 0.77 | CA12 (0.56) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL6372736 | 0.76 | CA12 (0.79) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627926-A1 | A method to reduce false positive results | Roche Diagnostics GmbH (DE) | 2006-02-22 | — | — | EP | disclosed |