Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.69 |
| ▸ | CYBB | P04839 | 1/20 | 0.64 |
| ▸ | HPN | P05981 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HSPA1A | P0DMV8 | 2/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.53 |
| ▸ | CD44 | P16070 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602307 | 0.88 | USP7 (0.87) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL17704810 | 0.84 | USP7 (0.73) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL15300175 | 0.82 | MAPT (0.78) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL25602301 | 0.82 | USP7 (0.80) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL16406028 | 0.81 | USP7 (1.00) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL15726783 | 0.81 | CA12 (0.76) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL17464656 | 0.81 | CA12 (0.76) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL14542508 | 0.81 | NR4A1 (0.80) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL25602294 | 0.80 | USP7 (0.67) | USP7CYBBHPNMAPTHSPA1A | |
| SCHEMBL31277265 | 0.78 | CYBB (1.00) | USP7CYBBHPNMAPTHSPA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |