Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.63 |
| ▸ | STS | P08842 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993530 | 0.90 | CYP19A1 (0.64) | CYP19A1STS | |
| SCHEMBL5992679 | 0.86 | CYP19A1 (0.65) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5991635 | 0.86 | CYP19A1 (0.60) | CYP19A1STS | |
| SCHEMBL5992772 | 0.86 | CYP19A1 (0.61) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5991035 | 0.85 | CYP19A1 (0.67) | CYP19A1STS | |
| SCHEMBL5991945 | 0.84 | CYP19A1 (0.68) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5991700 | 0.82 | CYP19A1 (0.80) | CYP19A1STS | |
| SCHEMBL5991732 | 0.80 | CYP19A1 (0.61) | CYP19A1STS | |
| SCHEMBL5995418 | 0.79 | CYP19A1 (0.73) | CYP19A1STSCYP11B1CYP11B2 | |
| SCHEMBL5992833 | 0.79 | CYP19A1 (0.62) | CYP19A1STSCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572665-B1 | 1-N-PHENYLAMINO-1H-IMIDAZOLE DERIVATIVES AS AROMATASE INHIBITORS | THERAMEX (MC) | 2006-05-03 | — | — | EP | disclosed |
| EP-1572665-A2 | 1-N-PHENYLAMINO-1H-IMIDAZOLE DERIVATIVES AS AROMATASE INHIBITORS | LABORATOIRE THERAMEX (MC) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054983-A2 | 1-N-PHENYLAMINO-1H-IMIDAZOLE DERIVATIVES AS AROMATASE INHIBITORS | LABORATOIRE THERAMEX (MC) | 2004-07-01 | — | — | WO | disclosed |
| EP-1431292-A1 | 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors | LABORATOIRE THERAMEX (MC) | 2004-06-23 | — | — | EP | disclosed |
| US-6737433-B1 | ESTROGEN DEPENDENT ANTITUMOR AGENTS | LABORATOIRE THERAMEX (MC) | 2004-05-18 | — | — | US | disclosed |