⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573282 | 0.78 | — | — | |
| SCHEMBL8355403 | 0.69 | — | — | |
| SCHEMBL6570936 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL95061 | 0.69 | — | — | |
| SCHEMBL424385 | 0.67 | — | — | |
| SCHEMBL95634 | 0.67 | — | — | |
| SCHEMBL18444 | 0.67 | — | — | |
| SCHEMBL95337 | 0.67 | — | — | |
| SCHEMBL1455312 | 0.67 | — | — | |
| SCHEMBL1530 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507673-B2 | Process for preparing 5,7 diaminopyrazolo [1,5-A] pyrimidine compounds | EMORY UNIVERSITY (US) | 2013-08-13 | — | — | US | disclosed |
| US-20120041198-A1 | Process for Preparing 5,7 Diaminopyrazolo [1,5-a] Pyrimidine Compounds | EMORY UNIVERSITY | 2012-02-16 | — | — | US | disclosed |
| WO-2010068838-A2 | PROCESSES FOR PREPARING 5,7 DIAMINOPYRAZOLO[1,5-α] PYRIMIDINE COMPOUNDS | EMORY UNIVERSITY (US) | 2010-06-17 | — | — | WO | disclosed |
| US-5827846-A | Carbazole derivatives as agents against multi-drug resistance | NOVARTIS CORP. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0637318-B1 | PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5686564-A | Peptide derivatives corresponding to the carboxy terminal sequence of hirudin | NOVARTIS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0763042-A1 | POLYCYCLIC LACTAM DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOUR AGENTS | Novartis AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| EP-0763040-A1 | CARBAZOLE DERIVATIVES AS AGENTS AGAINST MULTI-DRUG RESISTANCE | Novartis AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| EP-0763041-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | Novartis AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| EP-0548024-B1 | Aminosulphonic acid derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1997-01-08 | — | — | EP | disclosed |
| EP-0188400-A2 | Oligopeptides, intermediates and process for their preparation | CIBA-GEIGY AG (CH) | 1986-07-23 | — | — | EP | disclosed |
| US-4595677-A | Substituted tetrapeptides | CIBA-GEIGY CORPORATION (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0174912-A2 | Phosphorus compounds, process for their preparations and their use | CIBA-GEIGY AG (CH) | 1986-03-19 | — | — | EP | disclosed |
| EP-0169812-A1 | Phosphatidyl compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1986-01-29 | — | — | EP | disclosed |
| EP-0163286-A2 | Acylated sugars, method for their preparation and their use | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | disclosed |
| US-4508723-A | 6-Azaoligocycloalkylmethyleneaminopenam compounds | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| US-4505913-A | Substituted anthranilamides and pharmaceutical preparations containing these compounds | CIBA-GEIGY CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |
| EP-0111266-A2 | Substituted tetrapeptides | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |
| US-4423038-A | Phosphoryl compounds, pharmaceutical preparations containing such compounds, and their use | CIBA-GEIGY CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |