Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 9/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964372 | 1.00 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30GSK3BDYRK1A | |
| SCHEMBL1966893 | 1.00 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30GSK3BDYRK1A | |
| Hydrochloric Acid SCHEMBL1964562 | 0.99 | CHRNA7 (0.60) | CHRNA7HTR3AUSP30GSK3BDYRK1A | |
| Hydrochloric Acid SCHEMBL5470147 | 0.99 | CHRNA7 (0.60) | CHRNA7HTR3AUSP30GSK3BDYRK1A | |
| SCHEMBL1965419 | 0.93 | CHRNA7 (0.61) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL1965417 | 0.93 | CHRNA7 (0.61) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL1965401 | 0.93 | CHRNA7 (0.61) | CHRNA7HTR3AGSK3BDYRK1A | |
| Hydrochloric Acid SCHEMBL1967859 | 0.92 | CHRNA7 (0.60) | CHRNA7HTR3AGSK3BDYRK1A | |
| SCHEMBL1963552 | 0.84 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30 | |
| SCHEMBL5992868 | 0.84 | CHRNA7 (0.61) | CHRNA7HTR3AUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |