Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 14/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553481 | 1.00 | ADCY5 (0.54) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL30969135 | 1.00 | ADCY5 (0.54) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL5994918 | 1.00 | ADCY5 (0.54) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL7592748 | 1.00 | ADCY5 (0.54) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL7592747 | 1.00 | ADCY5 (0.54) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL6553491 | 1.00 | ADCY5 (0.54) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL7248842 | 0.85 | ADCY5 (0.55) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL5997270 | 0.84 | ADCY5 (0.74) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL5997273 | 0.84 | ADCY5 (0.74) | ADCY5NR1I2ALBPDE4DADORA2B | |
| SCHEMBL111590 | 0.84 | ADCY5 (0.74) | ADCY5NR1I2ALBPDE4DADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115590-B1 | Phosphoramidate, and mono-, di-, and tri-phosphate esters of (1R, cis)-4-(6-amino-9H-purin-9-yl)-2-cyclopentene-1-methanol as antiviral agents | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2006-10-03 | — | — | US | disclosed |
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | disclosed |