Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.67 |
| ▸ | HTR3A | P46098 | 3/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 13/20 | 0.49 |
| ▸ | GSK3B | P49841 | 10/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK3 | P49761 | 1/20 | 0.47 |
| ▸ | WNT1 | P04628 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965364 | 1.00 | CHRNA7 (0.67) | CHRNA7HTR3ADYRK1AGSK3BCLK2 | |
| SCHEMBL1963569 | 1.00 | CHRNA7 (0.67) | CHRNA7HTR3ADYRK1AGSK3BCLK2 | |
| SCHEMBL1966630 | 0.92 | CHRNA7 (0.67) | CHRNA7HTR3ADYRK1AGSK3BHTR3E | |
| SCHEMBL1966979 | 0.92 | CHRNA7 (0.67) | CHRNA7HTR3ADYRK1AGSK3BHTR3E | |
| SCHEMBL29749352 | 0.89 | CHRNA7 (0.66) | CHRNA7HTR3ADYRK1AGSK3BWNT1 | |
| SCHEMBL1458602 | 0.89 | CHRNA7 (0.66) | CHRNA7HTR3ADYRK1AGSK3BWNT1 | |
| SCHEMBL1459354 | 0.89 | CHRNA7 (0.66) | CHRNA7HTR3ADYRK1AGSK3BWNT1 | |
| SCHEMBL1459315 | 0.89 | CHRNA7 (0.66) | CHRNA7HTR3ADYRK1AGSK3BWNT1 | |
| Hydrochloric Acid SCHEMBL14797270 | 0.89 | CHRNA7 (0.65) | CHRNA7HTR3ADYRK1AGSK3BWNT1 | |
| Hydrochloric Acid SCHEMBL1966489 | 0.89 | CHRNA7 (0.65) | CHRNA7HTR3ADYRK1AGSK3BWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |