Butyric Acid

Butyric Acid

SCHEMBL59956

CCCC(=O)O.CCCCCC

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.81
HDAC3 O15379 1/20 0.81
HDAC1 Q13547 1/20 0.81
HDAC2 Q92769 1/20 0.81
HDAC8 Q9BY41 1/20 0.81
AKR1B1 P15121 1/20 0.78
GPR84 Q9NQS5 7/20 0.74
PPARG P37231 7/20 0.74
PPARD Q03181 7/20 0.74
PPARA Q07869 7/20 0.74
HDAC11 Q96DB2 5/20 0.74
TSHR P16473 4/20 0.74
PTPN1 P18031 3/20 0.74
FABP4 P15090 3/20 0.74
ALDH1A1 P00352 2/20 0.74
TLR2 O60603 2/20 0.74
TDP1 Q9NUW8 2/20 0.74
KMT2A Q03164 2/20 0.74
ALOX15 P16050 2/20 0.74
HSD17B10 Q99714 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL8661684 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4523506 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4229756 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL6418455 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL7471228 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL2807771 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL23014527 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL3077105 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL7462002 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4523509 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7511 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3440065-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE BERAPROST EUROAPI HUNGARY LLC (HU) 2022-06-08 EP claimed
EP-2987799-B1 ESTER DERIVATIVE OF 7-ALPHA-[9-(4,4,5,5,5-PENTAFLUOROPENTYLSULPHINYL)NONYL]OESTRA-1,3,5(10)-TRIENE-3,17BETA-DIOL HAVING ANTITUMOUR ACTIVITY AND PREPARATION METHOD THEREOF XIAN LIBANG PHARMACEUTICAL TECH CO LTD (CN) 2020-04-08 EP claimed
CN-106432385-B A kind of Preparation method and use of high-purity Breviscapinun extract and preparation 哈尔滨理工大学 2019-02-26 CN claimed
CN-109071463-A Novel form of sulfentrazone, process for its preparation and its use 江苏龙灯化学有限公司 2018-12-21 CN claimed
CN-108699010-A The new model of amicarbazone, Its Preparation Method And Use 江苏龙灯化学有限公司 2018-10-23 CN claimed
US-RE47078-E1 Polymorphic forms of N-[4-(trifluoromethyl)benzyl]-4-methoxybutyramide LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) 2018-10-09 US claimed
CN-108299274-A A kind of natural indoles, preparation method and application 中国热带农业科学院海口实验站 2018-07-20 CN claimed
CN-108137540-A Enantiomers of 8-hydroxyquinoline derivatives and synthesis thereof 艾维丁股份有限公司 2018-06-08 CN claimed
EP-3268357-A1 ENANTIOMERS OF 8-HYDROXY QUINOLINE DERIVATIVES AND THE SYNTHESIS THEREOF Avidin Co. Ltd. (HU) 2018-01-17 EP claimed
CN-107090353-A A kind of method for reducing glycidol ester content in refined vegetable grease 辽宁晟麦实业股份有限公司 2017-08-25 CN claimed
WO-2002079180-A1 A METHOD FOR CONVERTING DIHYDROTAGETONE, A BIFUNCTIONAL ACYCLIC MONOTERPENE KETONE INTO 5-ISOBUTYL-3-METHYL-4,5-DIHYDRO-2(3H)-FURANONE AS A ANALOGUE OF NATURAL WHISKY LACTONE AND COCONUT ALDEHYDE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-10-10 WO claimed
EP-1245570-A1 Process for the production of (-) 3,4 divanillyl tetrahydrofuran Council of Scientific and Industrial Research (IN) 2002-10-02 EP claimed
US-20020137949-A1 Novel method for converting dihydrotagetone, a bifuctional acyclic monoterpene ketone, isolated from the plant species of tagetes, into a coconut flavoured two chiral centered compound 5-isobutyl-3-methyl-4,5-dihydro-2(3H)-furanone as a novel analogue of natural whisky lactone and coconut aldehyde COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2002-09-26 US claimed
EP-0941219-B1 INTERMEDIATE FOR USE IN DOCETAXEL SYNTHESIS AND PRODUCTION METHOD THEREFOR NAPRO BIOTHERAPEUTICS INC (US) 2002-08-14 EP claimed
WO-2002038555-A1 ISOLATION OF TAXANES SAIJI LAHU (CA) 2002-05-16 WO claimed
US-6372922-B1 ISOLATING (-) SECOISOLARICIRESINOL FROM HEARTWOOD AND ROOTS OF TAXUS WALLICHIANA, DISSOLVING IN ORGANIC SOLVENT, REACTING WITH TRIPHENYL PHOSPHINE HALIDE, ISOLATING (-) 3,4-DIVANILLYL TETRAHYDROFURAN BY COLUMN CHROMATOGRAPHY COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-04-16 US claimed
WO-2001052902-A1 ANTISENSE MODULATION OF INDUCIBLE NITRIC OXIDE SYNTHASE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 2001-07-26 WO claimed
US-5476909-A Triblock copolymer,end block of polylactide, polyglycolide or copolymer, middle block of succinic acid modified polyoxyethylene glycol; improved hydrogel material SAM YANG CO., LTD. (KR) 1995-12-19 US claimed
EP-0493346-B1 Derivatives of 1,2,3,4-tetrahydronaphtylamine endowed with nootropic activity and pharmaceutical compositions containing same SIGMA TAU IND FARMACEUTI (IT) 1995-06-14 EP claimed
CN-85105898-A With the manufacture method that is 2-benzyl-4-(4-pyridine radicals) thiazoles He its derivative of immunomodulator 1987-01-21 CN claimed