SCHEMBL5997263

SCHEMBL5997263

COc1cccc(OC)c1C(=O)P(=O)(CC(C)CC(C)(C)C)C1CCCC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.38
DRD2 P14416 1/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
HCRTR1 O43613 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
HCRTR2 O43614 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5994279 0.99 POLB (0.44) POLBL3MBTL1DRD2HPGDALDH1A1
SCHEMBL5994569 0.86 POLB (0.44) POLBL3MBTL1DRD2HPGDALDH1A1
SCHEMBL5996810 0.84 POLB (0.46) POLBL3MBTL1DRD2HPGDALDH1A1
SCHEMBL5997076 0.82 CA12 (0.41) POLBALDH1A1CA12CA1CA2
SCHEMBL15237 0.82 CA12 (0.41) POLBALDH1A1CA12CA1CA2
Phosphine SCHEMBL28321500 0.81 CA12 (0.41) POLBALDH1A1CA12CA1CA2
SCHEMBL5997250 0.81 CA12 (0.41) POLBALDH1A1CA12CA1CA2
SCHEMBL5997951 0.80 CA12 (0.40) POLBALDH1A1CA12CA1CA2
SCHEMBL5996546 0.80 CA12 (0.40) POLBALDH1A1CA12CA1CA2
SCHEMBL5994669 0.79 POLB (0.47) POLBL3MBTL1DRD2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 POLB 1422/4885L3MBTL1 1852/4885DRD2 311/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 POLB 4477/4885L3MBTL1 1879/4885DRD2 943/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 POLB 2705/4885L3MBTL1 2570/4885DRD2 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.