SCHEMBL599995

SCHEMBL599995

O=C(O)c1ccc(CCCO)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.61
CYP4A11 Q02928 2/20 0.61
ALDH1A1 P00352 2/20 0.58
MEN1 O00255 1/20 0.58
RARA P10276 1/20 0.58
MAPT P10636 1/20 0.58
MTOR P42345 1/20 0.58
KMT2A Q03164 1/20 0.58
CYP4F2 P78329 1/20 0.55
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
TBXAS1 P24557 2/20 0.50
PPARA Q07869 1/20 0.50
CA2 P00918 1/20 0.50
HSD17B10 Q99714 1/20 0.48
PTGER1 P34995 1/20 0.47
PTGER4 P35408 1/20 0.47
PTGER3 P43115 1/20 0.47
PTGER2 P43116 1/20 0.47
HDAC8 Q9BY41 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2284179 0.94 RARB (0.62) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL1262098 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL5383508 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL31124203 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL8913329 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL6473001 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL1561875 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL6473267 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL3442617 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA
SCHEMBL31124115 0.92 RARB (0.64) RARBCYP4A11ALDH1A1MEN1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10906933-B2 Coupled peptide chain for dissolving poorly soluble polypeptides and application thereof for separation and purification in liquid chromatography SPEC-CHEM INDUSTRY INC. (CN) 2021-02-02 US claimed
CN-111655251-A Esters of hydroxybenzoic acids for the treatment of rhinoviruses 酶公司 2020-09-11 CN claimed
US-20180186830-A1 COUPLED PEPTIDE CHAIN FOR DISSOLVING POORLY SOLUBLE POLYPEPTIDES AND APPLICATION THEREOF FOR SEPARATION AND PURIFICATION IN LIQUID CHROMATOGRAPHY SPEC-CHEM INDUSTRY INC. (CN) 2018-07-05 US claimed
CN-105001298-B A kind of synthesis isolation and purification method of indissoluble polypeptide 南京斯拜科生化实业有限公司 2018-01-02 CN claimed
CN-105001307-A Coupling peptide chain capable of dissolving indissolvable polypeptide and application of the same in separation and purification in liquid chromatogram SPEC CHEM INDUSTRY INC 2015-10-28 CN claimed
CN-105001298-A Synthesis-separation and purification method for indissolvable polypeptide SPEC CHEM INDUSTRY INC 2015-10-28 CN claimed
EP-2667897-A1 PARABEN COMPOSITIONS Anterios, Inc. (US) 2013-12-04 EP claimed
US-20120321571-A1 PARABEN COMPOSITIONS ANTERIOS, INC. (US) 2012-12-20 US claimed
WO-2012103040-A1 PARABEN COMPOSITIONS ANTERIOS, INC. (US) 2012-08-02 WO claimed
EP-1368016-B1 PARENTERAL DOSAGE FORMS COMPRISING A SUSPENSION OF TRAMADOL SALT AND DICLOFENAC SALT GRUENENTHAL GMBH (DE) 2006-04-19 EP claimed
EP-1368016-A1 PARENTERAL DOSAGE FORMS COMPRISING A SUSPENSION OF TRAMADOL SALT AND DICLOFENAC SALT Grünenthal GmbH (DE) 2003-12-10 EP claimed
WO-2002043723-A1 PARENTERAL DOSAGE FORMS COMPRISING A SUSPENSION OF TRAMADOL SALT AND DICLOFENAC SALT Grünenthal GmbH (DE) 2002-06-06 WO claimed
JP-7075666-A None JP disclosed
EP-4692041-A1 METHOD FOR PRODUCING BIO-DERIVED ESTER COMPOUND, BIO-DERIVED ESTER COMPOUND PRODUCED THEREBY, COSMETIC OR DETERGENT CONTAINING BIO-DERIVED ESTER COMPOUND, AND METHOD FOR REDUCING ODOR OF ESTER COMPOUND ADEKA CORPORATION (JP) 2026-02-11 EP disclosed
US-12479797-B2 Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors Jubilant Epicore LLC (US) 2025-11-25 US disclosed
EP-3455204-B1 CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS Jubilant Epicore LLC (US) 2025-10-29 EP disclosed
US-4711900-A LIPOXYGENASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1987-12-08 US disclosed
US-4649044-A DISCOLORATION INHIBITION LION CORPORATION (JP) 1987-03-10 US disclosed
US-4466954-A CONTAINING DESTRANASE LION CORPORATION (JP) 1984-08-21 US disclosed
US-4024131-A ANTIINFLAMMATORY PLURICHEMIE ANSTALT (FL) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479797-B2 Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors HDAC1, HDAC11, HDAC2 RARB 1947/4885CYP4A11 654/4885ALDH1A1 821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.