Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 7/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999994 | 0.84 | HTR2A (0.67) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL5999729 | 0.83 | AHR (0.49) | HTR2ASLC6A4KCNH2TRPM8AHR | |
| SCHEMBL6000529 | 0.75 | HTR2A (0.46) | SOS1HTR2ASLC6A4KCNH2TAAR1 | |
| SCHEMBL5998731 | 0.74 | PTGS1 (0.48) | SOS1HTR2ATHRATHRBTRPM8 | |
| SCHEMBL3483906 | 0.73 | AHR (0.44) | HTR2ASLC6A4THRATHRBAHR | |
| Formic Acid SCHEMBL5999487 | 0.71 | SOS1 (0.43) | SOS1HTR2ASLC6A4KCNH2TAAR1 | |
| SCHEMBL13548692 | 0.71 | AHR (0.51) | AHRLTA4HF7F3NR4A2 | |
| SCHEMBL5998643 | 0.69 | SOS1 (0.46) | SOS1HTR2ASLC6A4KCNH2TAAR1 | |
| SCHEMBL5502812 | 0.69 | SOS1 (0.47) | SOS1HTR2ASLC6A4KCNH2TRPM8 | |
| SCHEMBL5999724 | 0.68 | HTR2A (0.67) | HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | PFIZER INC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | HTR2B, HTR2C, HTR3B | SOS1 3837/4885HTR2A 7/4885SLC6A4 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.