Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.60 |
| ▸ | HTR2A | P28223 | 19/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000331 | 0.87 | HTR2A (0.42) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6000292 | 0.84 | HTR2A (0.58) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL5998641 | 0.79 | HTR2A (0.63) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL5838723 | 0.75 | HTR2A (0.78) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6000297 | 0.74 | SLC6A4 (0.39) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6000523 | 0.73 | HTR2A (0.67) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL5500981 | 0.71 | HTR2A (0.71) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL5501815 | 0.70 | SLC6A4 (0.50) | SLC6A4HTR2AKCNH2HRH3 | |
| SCHEMBL5999994 | 0.69 | HTR2A (0.67) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL5502807 | 0.67 | SLC6A4 (0.69) | SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | PFIZER INC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | HTR2B, HTR2C, HTR3B | SLC6A4 150/4885HTR2A 7/4885KCNH2 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.