Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24663779 | 0.77 | CYP2B6 (0.34) | NPC1CYP2B6 | |
| SCHEMBL25131531 | 0.76 | CYP2B6 (0.35) | NPC1CYP2B6 | |
| SCHEMBL178517 | 0.74 | CYP2B6 (0.33) | NPC1CYP2B6 | |
| SCHEMBL23336586 | 0.74 | CYP2B6 (0.38) | NPC1CYP2B6KMT2A | |
| SCHEMBL22871678 | 0.74 | CYP2B6 (0.38) | NPC1CYP2B6KMT2A | |
| SCHEMBL11587102 | 0.72 | CYP2B6 (0.37) | NPC1CYP2B6KMT2A | |
| SCHEMBL9925976 | 0.72 | CYP2B6 (0.37) | NPC1CYP2B6KMT2A | |
| SCHEMBL8508540 | 0.72 | CYP2B6 (0.37) | NPC1CYP2B6KMT2A | |
| SCHEMBL3634951 | 0.72 | CYP2D6 (0.33) | NPC1CYP2B6 | |
| SCHEMBL22485468 | 0.72 | CYP2B6 (0.32) | NPC1CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| EP-0138684-A2 | 2-(N-pyrrolidino)-3-isobutoxy-N-phenyl-substituted N-benzylpropyl amines, their preparation and their pharmaceutical use | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1985-04-24 | — | — | EP | disclosed |