Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001311 | 1.00 | PTGER4 (0.37) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5999437 | 0.93 | PTGER4 (0.33) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5999428 | 0.93 | PTGER4 (0.33) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6000414 | 0.88 | PTGER4 (0.38) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6000419 | 0.88 | PTGER4 (0.38) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6001331 | 0.88 | PTGER4 (0.45) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6001326 | 0.88 | PTGER4 (0.45) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6000576 | 0.85 | PTGER4 (0.38) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6001464 | 0.85 | PTGER4 (0.42) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6001468 | 0.85 | PTGER4 (0.42) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060258726-A1 | 1,5-Disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases | MERCK FROSST CANADA LTD. (CA) | 2006-11-16 | — | — | US | claimed |
| US-20060258726-A1 | 1,5-Disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases | MERCK FROSST CANADA LTD. (CA) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258726-A1 | 1,5-Disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases | PTGER4, PTGER1, PTGER2 | PTGER4 1/4885PTGER3 5/4885PTGER2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.