Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.55 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001375 | 0.90 | TRPV1 (0.52) | TRPV1BRS3FAAHMKNK1 | |
| SCHEMBL6001835 | 0.88 | TRPV1 (0.56) | TRPV1BRS3FAAH | |
| SCHEMBL4870065 | 0.87 | TRPV1 (0.54) | TRPV1BRS3FAAHMKNK1 | |
| SCHEMBL18910804 | 0.86 | HTR2A (0.49) | BRS3FAAHMKNK1 | |
| SCHEMBL4867533 | 0.85 | TRPV1 (0.56) | TRPV1BRS3FAAHMKNK1 | |
| SCHEMBL4866606 | 0.84 | TRPV1 (0.55) | TRPV1FAAHMKNK1 | |
| SCHEMBL4867524 | 0.84 | TRPV1 (0.49) | TRPV1BRS3FAAH | |
| SCHEMBL8253137 | 0.79 | TRPV1 (0.54) | TRPV1BRS3 | |
| SCHEMBL14086113 | 0.79 | TRPV1 (0.55) | TRPV1BRS3FAAH | |
| SCHEMBL4861662 | 0.79 | TRPV1 (0.56) | TRPV1BRS3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128710-A1 | Antagonists to the vanilloid receptor subtype 1 (VR1) and uses thereof | ABBOTT LABORATORIES | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128710-A1 | Antagonists to the vanilloid receptor subtype 1 (VR1) and uses thereof | OPRL1, AVPR1A, AVPR2 | TRPV1 5/4885BRS3 124/4885FAAH 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.