Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218133 | 0.83 | TLR8 (0.38) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL30402217 | 0.80 | GPBAR1 (0.42) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL3021081 | 0.79 | GPBAR1 (0.41) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL30746985 | 0.79 | GPBAR1 (0.41) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL30746954 | 0.78 | TLR8 (0.41) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL30402892 | 0.78 | TLR8 (0.41) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL30543224 | 0.78 | GPBAR1 (0.40) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL30543203 | 0.78 | TLR8 (0.41) | GPBAR1ALDH1A1MAPK1CYSLTR2CYSLTR1 | |
| SCHEMBL26479716 | 0.78 | CYP1A2 (0.40) | GPBAR1CYSLTR2CYSLTR1CYP1A2TLR8 | |
| SCHEMBL14505627 | 0.73 | CYP1A2 (0.42) | GPBAR1CYSLTR1CYP1A2TSHRTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | GPBAR1 3306/4885ALDH1A1 2033/4885MAPK1 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.