Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 18/20 | 0.88 |
| ▸ | ABCB1 | P08183 | 11/20 | 0.88 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.88 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22273241 | 0.94 | ABCG2 (1.00) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL16404295 | 0.92 | ABCG2 (1.00) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL6001931 | 0.92 | ABCG2 (0.93) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL16404294 | 0.87 | ABCG2 (0.86) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL4859258 | 0.83 | ABCG2 (0.80) | ABCG2ABCB1ABCC1MEN1KMT2A | |
| SCHEMBL6001826 | 0.81 | ACP1 (0.76) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL2256504 | 0.81 | ABCG2 (0.73) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL6001681 | 0.81 | ABCG2 (0.62) | ABCG2ABCB1ABCC1TP53MAPT | |
| SCHEMBL4868573 | 0.80 | ABCG2 (1.00) | ABCG2ABCC1TP53MAPTMEN1 | |
| SCHEMBL3112389 | 0.80 | ABCG2 (0.71) | ABCG2ABCB1ABCC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | ABCG2 2694/4885ABCB1 2698/4885ABCC1 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.