Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226841 | 1.00 | TACR1 (0.37) | TACR1AOC3NSD2TACR2HDAC6 | |
| SCHEMBL27649466 | 0.92 | TACR1 (0.34) | TACR1AOC3NSD2TACR2HDAC6 | |
| SCHEMBL4262915 | 0.92 | TACR1 (0.34) | TACR1AOC3NSD2TACR2HDAC6 | |
| SCHEMBL4259182 | 0.90 | TACR1 (0.49) | TACR1HDAC6 | |
| SCHEMBL493659 | 0.90 | TACR1 (0.49) | TACR1HDAC6 | |
| SCHEMBL4256188 | 0.89 | TACR1 (0.36) | TACR1AOC3NSD2TACR2HDAC6 | |
| SCHEMBL4256181 | 0.86 | TACR1 (0.37) | TACR1AOC3NSD2TACR2BCHE | |
| SCHEMBL6002625 | 0.86 | TACR1 (0.37) | TACR1AOC3NSD2TACR2BCHE | |
| SCHEMBL5450480 | 0.84 | TACR1 (0.38) | TACR1AOC3NSD2TACR2 | |
| SCHEMBL5450475 | 0.84 | TACR1 (0.38) | TACR1AOC3NSD2TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | claimed |
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |