⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049804 | 0.56 | — | — | |
| SCHEMBL9242823 | 0.56 | — | — | |
| SCHEMBL5707850 | 0.55 | — | — | |
| SCHEMBL31426425 | 0.55 | — | — | |
| SCHEMBL7709747 | 0.48 | — | — | |
| SCHEMBL10177686 | 0.48 | — | — | |
| SCHEMBL1900770 | 0.47 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL5697321 | 0.44 | — | — | |
| SCHEMBL8370302 | 0.42 | — | — | |
| SCHEMBL1221734 | 0.38 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025356-A1 | 28-epirapalogs | ARIAD PHARMACEUTICALS, INC. | 2006-02-02 | — | — | US | disclosed |
| US-6693189-B2 | NON-IMMUNOSUPPRESSIVE RAPAMYCIN DERIVATIVES | ARIAD GENE THERAPEUTICS, INC. | 2004-02-17 | — | — | US | disclosed |
| US-6649595-B2 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | ARIAD GENE THERAPEUTICS, INC. | 2003-11-18 | — | — | US | disclosed |
| EP-1212331-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001014387-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2001-03-01 | — | — | WO | disclosed |
| EP-1045915-A2 | REGULATION OF BIOLOGICAL EVENTS USING MULTIMERIC CHIMERIC PROTEINS | ARIAD GENE THERAPEUTICS, INC. (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999036553-A2 | REGULATION OF BIOLOGICAL EVENTS USING MULTIMERIC CHIMERIC PROTEINS | ARIAD GENE THERAPEUTICS, INC. (US) | 1999-07-22 | — | — | WO | disclosed |