Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.53 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003350 | 0.91 | SMN1; SMN2 (0.55) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL6001358 | 0.83 | UBE2T (0.56) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL19372016 | 0.80 | UBE2T (0.70) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL6510681 | 0.80 | SMN1; SMN2 (0.56) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL31595800 | 0.80 | SMN1; SMN2 (0.56) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL17385655 | 0.80 | UBE2T (0.56) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL8904885 | 0.78 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL9641726 | 0.77 | SMN1; SMN2 (0.70) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL2047532 | 0.75 | SMN1; SMN2 (0.62) | UBE2TASIC3SMN1; SMN2HTTALOX15 | |
| SCHEMBL6002793 | 0.74 | SMN1; SMN2 (0.57) | UBE2TASIC3SMN1; SMN2HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |