Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | BRD2 | P25440 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113778 | 0.97 | BRD4 (0.50) | BRD4BRD2LMNAPIK3CDTSHR | |
| SCHEMBL2363506 | 0.94 | BRD4 (0.48) | BRD4BRD2LMNAPIK3CDTSHR | |
| SCHEMBL3053956 | 0.91 | BRD4 (0.46) | BRD4BRD2LMNAPIK3CDTSHR | |
| SCHEMBL12443428 | 0.90 | BRD4 (0.43) | BRD4BRD2LMNAPIK3CDTSHR | |
| SCHEMBL1440028 | 0.90 | BRD4 (0.43) | BRD4BRD2LMNAPIK3CDTSHR | |
| SCHEMBL11382367 | 0.88 | BRD4 (0.42) | BRD4BRD2LMNAPIK3CDCHRM2 | |
| SCHEMBL14559892 | 0.87 | BRD4 (0.39) | BRD4BRD2LMNAPIK3CDTSHR | |
| SCHEMBL12450880 | 0.87 | CHRM2 (0.39) | BRD4BRD2LMNAPIK3CDCHRM2 | |
| SCHEMBL5339702 | 0.87 | BRD4 (0.42) | BRD4BRD2LMNAPIK3CDTSHR | |
| SCHEMBL1065591 | 0.83 | BRD4 (0.44) | BRD4BRD2LMNAPIK3CDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715988-A | Bipyrrolinone compounds | DIC株式会社 | 2024-03-15 | — | — | CN | claimed |
| US-20170204062-A1 | PROCESS FOR THE PREPARATION OF REGORAFENIB AND ITS CRYSTALLINE FORMS | SHILPA MEDICARE LIMITED (IN) | 2017-07-20 | — | — | US | claimed |
| EP-1131062-B1 | INJECTABLE PROPOFOL FORMULATIONS | VETERINARY RES ASSOCIATES INC (US) | 2005-01-26 | — | — | EP | claimed |
| CN-117715988-A | Bipyrrolinone compounds | DIC株式会社 | 2024-03-15 | — | — | CN | disclosed |
| CN-117715988-A | Bipyrrolinone compounds | DIC株式会社 | 2024-03-15 | — | — | CN | disclosed |
| WO-2024034957-A1 | ELECTROCHROMIC ELEMENT AND WINDOW DEVICE COMPRISING SAME | 에스케이씨 주식회사 | 2024-02-15 | — | — | WO | disclosed |
| CN-111344562-B | Compositions, methods, kits and devices for molecular analysis | 因特根克斯股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116368143-A | Nucleoside 5' -substituted monophosphates, prodrugs thereof, and uses thereof | 埃莫里大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-111372456-B | Herbicidally active pyridyl-/pyrimidinyl-pyrazine derivatives | 先正达参股股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| WO-2021095482-A1 | METHOD FOR PRODUCING POLYAMIDE, AND POLYAMIDE | 株式会社クレハ | 2021-05-20 | — | — | WO | disclosed |
| CN-109971340-A | A kind of antistatic antirust covers the preparation method of iron film | 常州市贝特织造有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-1086396-C | Preparation of water-soluble copolymers of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer | BASF AG (DE) | 2002-06-19 | — | — | CN | disclosed |
| EP-1168470-A1 | Hydrogen absorbing alloy electrode, method of fabricating the same and alkaline storage battery | SANYO ELECTRIC Co., Ltd. (JP) | 2002-01-02 | — | — | EP | disclosed |
| CN-1069898-C | Purification of N-vinylpyrrolidone by crystallization | BASF AG (DE) | 2001-08-22 | — | — | CN | disclosed |
| WO-1999055505-A1 | DIFFUSABLE ANTISAPSTAIN METHOD AND COMPOSITIONS | NEW ZEALAND FOREST RESEARCH INSTITUTE LIMITED (NZ) | 1999-11-04 | — | — | WO | disclosed |
| US-5753373-A | SUBSTRATE COATED WITH INORGANIC METAL OXIDE PARTICLES, NONIONIC SURFACTANTS; SURGICAL FACE, EYE SHIELDS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| CN-1163900-A | Preparation of water-soluble copolymers of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer | BASF AG (DE) | 1997-11-05 | — | — | CN | disclosed |
| EP-0500625-A1 | COMPOSITION FOR CLEANING AN INTERNAL COMBUSTION ENGINE | PETRO CHEMICAL PRODUCTS INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991007578-A1 | COMPOSITION FOR CLEANING AN INTERNAL COMBUSTION ENGINE | PETRO CHEMICAL PRODUCTS INC. (US) | 1991-05-30 | — | — | WO | disclosed |
| US-4997454-A | Precipitation | THE UNIVERSITY OF ROCHESTER (US) | 1991-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204062-A1 | PROCESS FOR THE PREPARATION OF REGORAFENIB AND ITS CRYSTALLINE FORMS | BRAF, ALK, NRAS | BRD4 1461/4885BRD2 1637/4885LMNA 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.