Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090219 | 0.88 | TAAR1 (0.50) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL2095940 | 0.87 | TAAR1 (0.51) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL2095553 | 0.85 | TAAR1 (0.53) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL2096778 | 0.85 | TAAR1 (0.53) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL2094806 | 0.84 | TAAR1 (0.51) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL11613337 | 0.82 | TAAR1 (0.61) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL18608715 | 0.81 | TAAR1 (0.56) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL1047345 | 0.81 | TAAR1 (0.59) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL1046263 | 0.80 | TAAR1 (0.62) | TAAR1HDAC1HDAC8IDO1MIF | |
| SCHEMBL3153651 | 0.79 | IDO1 (0.64) | TAAR1IDO1MIFHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |