Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.48 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003101 | 1.00 | TACR1 (0.48) | TACR1RHOCRHOAKCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL5368530 | 0.99 | TACR1 (0.48) | TACR1RHOCRHOAKCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL5368523 | 0.99 | TACR1 (0.48) | TACR1RHOCRHOAKCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL5369016 | 0.89 | TACR1 (0.47) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL6003074 | 0.89 | TACR1 (0.45) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5526636 | 0.89 | TACR1 (0.45) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5366774 | 0.89 | TACR1 (0.45) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5366243 | 0.87 | TACR1 (0.43) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5366235 | 0.87 | TACR1 (0.43) | TACR1RHOCRHOA | |
| SCHEMBL5360994 | 0.86 | TACR1 (0.53) | TACR1RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140924-B1 | PIPERAZINE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2006-03-22 | — | — | EP | disclosed |