Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 18/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634484 | 1.00 | CFTR (0.50) | CFTRKMT2ACDK8NTRK3 | |
| SCHEMBL5635489 | 0.93 | CFTR (0.51) | CFTRKMT2ACDK8NTRK3 | |
| SCHEMBL6003560 | 0.93 | CFTR (0.51) | CFTRKMT2ACDK8NTRK3 | |
| SCHEMBL6003860 | 0.92 | CFTR (0.52) | CFTRKMT2A | |
| SCHEMBL5634673 | 0.92 | CFTR (0.52) | CFTRKMT2A | |
| SCHEMBL5635694 | 0.90 | CFTR (0.53) | CFTRKMT2A | |
| SCHEMBL6003573 | 0.90 | CFTR (0.53) | CFTRKMT2A | |
| SCHEMBL5634918 | 0.90 | CFTR (0.50) | CFTRKMT2A | |
| SCHEMBL6003618 | 0.89 | KMT2A (0.52) | CFTRKMT2A | |
| Trifluoroacetic Acid SCHEMBL5661939 | 0.89 | CFTR (0.47) | CFTRKMT2ACDK8NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006122931-A1 | BETA-CARBOLINE DERIVATIVES AND THERI USE AS GHSR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2006-11-23 | — | — | WO | claimed |