SCHEMBL6003623

SCHEMBL6003623

O=[N+]([O-])c1ccc(N2CCCC2CO)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.55
▸ ALDH1A1 P00352 4/20 0.53
▸ LMNA P02545 1/20 0.53
▸ ALOX12 P18054 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ CYP1A2 P05177 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ CUL4A Q13619 1/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ MEN1 O00255 4/20 0.46
▸ KMT2A Q03164 4/20 0.46
▸ ATM Q13315 1/20 0.46
▸ NPBWR1 P48145 1/20 0.44
▸ MCHR1 Q99705 1/20 0.44
▸ NPY2R P49146 1/20 0.43
▸ MAPK1 P28482 1/20 0.42
▸ CRBN Q96SW2 2/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5822677 1.00 MAPT (0.55) MAPTALDH1A1LMNAALOX12NPSR1
SCHEMBL29713599 1.00 MAPT (0.55) MAPTALDH1A1LMNAALOX12NPSR1
SCHEMBL9785920 0.81 MAPT (0.56) MAPTALDH1A1LMNAALOX12NPSR1
SCHEMBL26633289 0.80 MAPT (0.63) MAPTALDH1A1LMNAALOX12NPSR1
SCHEMBL26633283 0.80 MAPT (0.63) MAPTALDH1A1LMNAALOX12NPSR1
SCHEMBL26633342 0.80 MAPT (0.63) MAPTALDH1A1LMNAALOX12NPSR1
SCHEMBL10898231 0.80 MAPT (0.58) MAPTALDH1A1LMNAALOX12NPSR1
SCHEMBL223024 0.80 MAPT (0.47) MAPTALDH1A1CUL4APOLBMAPK1
SCHEMBL5653005 0.80 MAPT (0.47) MAPTALDH1A1CUL4APOLBMAPK1
SCHEMBL1092846 0.80 MAPT (0.47) MAPTALDH1A1CUL4APOLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0186999-B1 OPTICAL COMPOSITIONS BRITISH TELECOMMUNICATIONS public limited company (GB) 1989-03-15 — — EP claimed
US-4746577-A VINYLIDENE FLUORIDE COPOLYMER AND OPTOELECTRONIC ADDITIVE BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY (GB) 1988-05-24 — — US claimed
WO-2023036103-A1 CONSTRUCTION OF SULFONATION MODIFICATION SYSTEM FOR PREPARATION OF HEPARINS HAVING DIFFERENT MOLECULAR WEIGHTS, AND APPLICATION THEREOF 江南大学 2023-03-16 — — WO disclosed
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 — — US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 — — US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 — — US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 — — US disclosed
EP-0186999-B1 OPTICAL COMPOSITIONS BRITISH TELECOMMUNICATIONS public limited company (GB) 1989-03-15 — — EP disclosed
US-4748074-A WAVEGUIDES BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY (GB) 1988-05-31 — — US disclosed
US-4746577-A VINYLIDENE FLUORIDE COPOLYMER AND OPTOELECTRONIC ADDITIVE BRITISH TELECOMMUNICATIONS PUBLIC LIMITED COMPANY (GB) 1988-05-24 — — US disclosed
EP-0186999-A1 Optical compositions BRITISH TELECOMMUNICATIONS public limited company (GB) 1986-07-09 — — EP disclosed
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