SCHEMBL6003671

SCHEMBL6003671

CNC(=O)c1c(C(=O)O)c2c(C(=O)O)ccc3c4cccc5cccc(c(c1C(=O)NC)c23)c54

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLK1 P53350 2/20 0.42
▸ HSD17B10 Q99714 7/20 0.39
▸ ALDH1A1 P00352 6/20 0.38
▸ KDM4E B2RXH2 5/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ HPGD P15428 4/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ GLA P06280 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ NR4A1 P22736 1/20 0.36
▸ NR4A2 P43354 1/20 0.36
▸ NR4A3 Q92570 1/20 0.36
▸ CDC25B P30305 1/20 0.36
▸ WDR5 P61964 1/20 0.35
▸ MEN1 O00255 3/20 0.34
▸ RXFP1 Q9HBX9 2/20 0.34
▸ LDHA P00338 1/20 0.34
▸ PGR P06401 1/20 0.34
▸ GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9616217 0.97 PLK1 (0.42) PLK1HSD17B10ALDH1A1KDM4EKMT2A
SCHEMBL9321447 0.92 PLK1 (0.46) PLK1HSD17B10ALDH1A1KDM4EKMT2A
Ammonia Solution, Strong SCHEMBL11928228 0.88 HSD17B10 (0.46) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL31542978 0.86 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL29450079 0.86 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL186130 0.86 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL28062062 0.86 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL2212717 0.85 MEN1 (0.43) HSD17B10ALDH1A1KDM4EKMT2APOLB
SCHEMBL14637543 0.85 HSD17B10 (0.46) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL31596274 0.85 HSD17B10 (0.46) HSD17B10ALDH1A1KDM4EKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2474026-B1 CURRENT-AMPLIFYING TRANSISTOR DEVICE AND CURRENT-AMPLIFYING, LIGHT-EMITTING TRANSISTOR DEVICE DAINICHISEIKA COLOR CHEM (JP) 2018-12-12 — — EP claimed
US-20120146011-A1 Current-Amplifying Transistor Device and Current-Amplifying, Light-Emitting Transistor Device KEN-ICHI NAKAYAMA (JP) 2012-06-14 — — US claimed
EP-2474026-B1 CURRENT-AMPLIFYING TRANSISTOR DEVICE AND CURRENT-AMPLIFYING, LIGHT-EMITTING TRANSISTOR DEVICE DAINICHISEIKA COLOR CHEM (JP) 2018-12-12 — — EP disclosed
US-8927972-B2 Current-amplifying transistor device and current-amplifying, light-emitting transistor device DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2015-01-06 — — US disclosed
US-20120146011-A1 Current-Amplifying Transistor Device and Current-Amplifying, Light-Emitting Transistor Device KEN-ICHI NAKAYAMA (JP) 2012-06-14 — — US disclosed
EP-1414912-B1 PERYLENE PIGMENT COMPOSITIONS SUN CHEMICAL CORP (US) 2006-10-04 — — EP disclosed
EP-1010731-B1 Process for the preparation of highly chromatic perylene pigments SUN CHEMICAL CORP (US) 2004-11-03 — — EP disclosed
EP-1414912-A2 PERYLENE PIGMENT COMPOSITIONS SUN CHEMICAL CORPORATION (US) 2004-05-06 — — EP disclosed
EP-1020496-B1 Process for the preparation of highly coloured chromatic perylene pigments SUN CHEMICAL CORP (US) 2004-03-31 — — EP disclosed
US-6692562-B2 IMIDATION OF PERYLENETETRACARBOXYLIC ACID DERIVATIVE; ALKYLATION SUN CHEMICAL CORPORATION 2004-02-17 — — US disclosed
US-20030167971-A1 Process for making perylene pigment compositions SUN CHEMICAL CORPORATION 2003-09-11 — — US disclosed
US-6153764-A IMIDATION OF A PERYLENE TETRACARBOXYLIC DERIVATIVE PIGMENT PRECURSOR BY CYCLIZATION REACTION WITH AMMONIA OR AN AMINE IN SOLUTION OF REACTION MIXTURE CONTAINING A SECOND CYCLIC IMIDE DERIVATIVE WHICH IS NON-PIGMENTARY BAYER CORPORATION (US) 2000-11-28 — — US disclosed
US-6143068-A PREPARED BY REACTING A PERYLENE TETRACARBOXYLIC COMPOUND WITH A NON-PIGMENTARY CYCLIC ANHYDRIDE AND AMMONIA OR A PRIMARY AMINE; ACID RESISTANCE, ALKALI RESISTANCE, HEAT RESISTANCE BAYER CORPORATION (US) 2000-11-07 — — US disclosed
EP-1020496-A1 Process for the preparation of highly chromatic perylene pigments Bayer Corporation (US) 2000-07-19 — — EP disclosed
EP-1010731-A2 Process for the preparation of highly chromatic perylene pigments Bayer Corporation (US) 2000-06-21 — — EP disclosed
US-6039769-A Process for the preparation of highly chromatic perylene pigments BAYER CORPORATION (US) 2000-03-21 — — US disclosed
US-6015458-A Process for the preparation of highly chromatic perylene pigments BAYER CORPORATION (US) 2000-01-18 — — US disclosed
EP-0851006-A1 Organic pigment compositions Bayer Corporation (US) 1998-07-01 — — EP disclosed
US-5711800-A Organic pigment compositions BAYER CORPORATION (US) 1998-01-27 — — US disclosed
US-5126504-A Easily strippable HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030167971-A1 Process for making perylene pigment compositions ATXN2L, HACL2, TYR PLK1 4869/4885HSD17B10 465/4885ALDH1A1 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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