Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 14/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 12/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004454 | 0.90 | CSNK1E (0.47) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL6004040 | 0.89 | CSNK1E (0.50) | CSNK1ECSNK1DMAPK14MAP4K4TNIK | |
| SCHEMBL4719200 | 0.88 | MAPK14 (0.52) | CSNK1ECSNK1DMAPK14MAP4K4 | |
| SCHEMBL4721256 | 0.82 | TLR7 (0.46) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL4723796 | 0.80 | BRD4 (0.45) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL6002781 | 0.80 | CSNK1E (0.47) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL4825008 | 0.79 | MAPK14 (0.54) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL6004451 | 0.78 | CSNK1D (0.48) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL6003859 | 0.78 | MAPK14 (0.54) | CSNK1ECSNK1DMAPK14 | |
| SCHEMBL4760720 | 0.77 | MAPK14 (0.51) | CSNK1ECSNK1DMAPK14MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | KALYPSYS, INC. | 2006-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252807-A1 | Novel ortho-terphenyl inhibitors of p38 kinase and methods of treating inflammatory disorders | MAPK1, MAP3K1, MAPK4 | CSNK1E 1579/4885CSNK1D 1696/4885MAPK14 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.