Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 18/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6003305 | 0.99 | CHEK2 (0.43) | CHEK2ESR1ESR2 | |
| SCHEMBL6004620 | 0.93 | CHEK2 (0.44) | CHEK2ESR1ESR2 | |
| SCHEMBL6005357 | 0.93 | CHEK2 (0.43) | CHEK2ESR1ESR2 | |
| SCHEMBL6003362 | 0.92 | CHEK2 (0.43) | CHEK2ESR1ESR2 | |
| SCHEMBL6004626 | 0.92 | CHEK2 (0.44) | CHEK2ESR1ESR2 | |
| SCHEMBL6005869 | 0.92 | CHEK2 (0.44) | CHEK2ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL6003391 | 0.91 | CHEK2 (0.43) | CHEK2ESR1ESR2 | |
| SCHEMBL6003282 | 0.91 | CHEK2 (0.43) | CHEK2ESR1ESR2 | |
| SCHEMBL6004724 | 0.91 | CHEK2 (0.43) | CHEK2ESR1ESR2 | |
| SCHEMBL6005679 | 0.91 | CHEK2 (0.44) | CHEK2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709021-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS FOR THE TREATMENT OF VASOMOTOR SYMPTOMS | ELI LILLY AND COMPANY (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005073204-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS FOR THE TREATMENT OF VASOMOTOR SYMPTOMS | ELI LILLY AND COMPANY (US) | 2005-08-11 | — | — | WO | disclosed |