Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 3/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004159 | 0.91 | FGFR2 (0.52) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL3893058 | 0.89 | FGFR2 (0.56) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL3895567 | 0.87 | PDGFRB (0.49) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL3896885 | 0.86 | PDGFRB (0.50) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL6004624 | 0.84 | PDGFRB (0.50) | FGFR2PDGFRAPDGFRBEGFRKDR | |
| SCHEMBL6004008 | 0.83 | PDGFRB (0.52) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL3902626 | 0.82 | FGFR2 (0.51) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL3895779 | 0.81 | FGFR2 (0.53) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL3906131 | 0.81 | SRC (0.55) | FGFR2SRCTGFBR1PDGFRAPDGFRB | |
| SCHEMBL3894993 | 0.80 | KDR (0.49) | FGFR2SRCTGFBR1PDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |