Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.59 |
| ▸ | PPARA | Q07869 | 14/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21881525 | 1.00 | PPARG (0.59) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL11185611 | 0.95 | PPARG (0.57) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL11752505 | 0.93 | PPARG (0.67) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL14889080 | 0.93 | PPARG (0.67) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL934313 | 0.93 | PPARG (0.61) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL11378771 | 0.91 | PPARG (0.55) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL11565502 | 0.90 | PPARG (0.60) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL11563937 | 0.90 | PPARG (0.60) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL11566109 | 0.88 | PPARG (0.57) | PPARGPPARAMEN1POLBCASP3 | |
| SCHEMBL11574826 | 0.87 | PPARG (0.57) | PPARGPPARAMEN1POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520176-B1 | Method for increasing the nutritional value of rapeseed and rape products with decreased oil content | ROP REPCE OLAJ PELLET KFT (HU) | 2019-02-20 | — | — | EP | disclosed |
| US-20120282369-A1 | METHOD FOR INCREASING THE NUTRITIONAL VALUE OF RAPESEED AND RAPE PRODUCTS WITH DECREASED OIL CONTENT | ROP REPCE-OLAJ-PELLET KFT. (HU) | 2012-11-08 | — | — | US | disclosed |
| EP-2520176-A1 | Method for increasing the nutritional value of rapeseed and rape products with decreased oil content | ROP Repce-olaj-pellet Kft. (HU) | 2012-11-07 | — | — | EP | disclosed |
| US-7105509-B2 | Benzodiazepine derivatives as APP modulators | MERCK SHARP & DOHME LIMITED (GB) | 2006-09-12 | — | — | US | disclosed |
| US-20040082572-A1 | Benzodiazepine derivatives as app modulators | MERCK SHARPE & DOHME LIMITED (GB) | 2004-04-29 | — | — | US | disclosed |
| EP-1294702-A1 | BENZODIAZEPINE DERIVATIVES AS APP MODULATORS | MERCK SHARP & DOHME LTD. (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001090084-A1 | BENZODIAZEPINE DERIVATIVES AS APP MODULATORS | MERCK SHARP & DOHME LIMITED (GB) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082572-A1 | Benzodiazepine derivatives as app modulators | BACE1, PSEN1, APP | PPARG 255/4885PPARA 350/4885MEN1 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.