Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456305 | 0.95 | CNR1 (0.66) | CNR1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL12789540 | 0.83 | CNR1 (0.77) | CNR1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL3400921 | 0.81 | CNR1 (0.66) | CNR1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL12789085 | 0.80 | CNR1 (0.72) | CNR1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL12790042 | 0.80 | CNR1 (0.72) | CNR1SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL3405391 | 0.80 | CNR1 (0.65) | CNR1SMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL3403003 | 0.80 | CNR1 (0.65) | CNR1SMN1; SMN2ALDH1A1NPSR1LMNA | |
| SCHEMBL915960 | 0.76 | CNR1 (0.62) | CNR1SMN1; SMN2ALDH1A1MAPTNPSR1 | |
| SCHEMBL17773239 | 0.75 | CNR1 (0.53) | CNR1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL3454733 | 0.74 | SIGLEC9 (0.47) | CNR1ALDH1A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615698-A2 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | NOVO NORDISK A/S (DK) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089470-A2 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |