Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509208 | 1.00 | CYP2D6 (0.45) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL23992776 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL4506501 | 0.76 | CYP2D6 (0.50) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL7493871 | 0.75 | CYP2D6 (0.40) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL7497625 | 0.75 | CYP2D6 (0.40) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL7492577 | 0.75 | CYP2D6 (0.40) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL4506500 | 0.71 | CYP2D6 (0.45) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL6007971 | 0.71 | CYP2D6 (0.45) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL3816525 | 0.71 | KMT2A (0.42) | CYP2D6MC4RKMT2AOPRM1OPRK1 | |
| SCHEMBL4128850 | 0.71 | KMT2A (0.42) | CYP2D6MC4RKMT2AOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924213-B1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2006-06-28 | — | — | EP | disclosed |
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6191129-B1 | MICROBIOCIDES, BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0924213-A1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |