SCHEMBL6007833

SCHEMBL6007833

Nc1cc2cccc(C(=O)O)c2cc1N

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.58
PTPN1 P18031 1/20 0.58
NR4A1 P22736 1/20 0.57
NR4A2 P43354 1/20 0.57
NR4A3 Q92570 1/20 0.57
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 4/20 0.50
GAA P10253 2/20 0.50
MMP2 P08253 1/20 0.50
GRIN2D O15399 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49
CDC25B P30305 3/20 0.46
HSD17B10 Q99714 3/20 0.46
G6PD P11413 1/20 0.46
CASP7 P55210 1/20 0.46
CASP6 P55212 1/20 0.46
HPGD P15428 3/20 0.44
KMT2A Q03164 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71960 0.86 NR4A1 (0.68) IDO1PTPN1NR4A1NR4A2NR4A3
SCHEMBL29600450 0.86 NR4A1 (0.68) IDO1PTPN1NR4A1NR4A2NR4A3
Hydrochloric Acid SCHEMBL4607125 0.84 PTPN1 (0.66) IDO1PTPN1NR4A1NR4A2NR4A3
SCHEMBL71261 0.84 PTPN1 (0.66) IDO1PTPN1NR4A1NR4A2NR4A3
SCHEMBL30367135 0.84 PTPN1 (0.66) IDO1PTPN1NR4A1NR4A2NR4A3
Hydrochloric Acid SCHEMBL6847145 0.82 PTPN1 (0.63) IDO1PTPN1NR4A1NR4A2NR4A3
SCHEMBL31401749 0.82 PTPN1 (0.63) IDO1PTPN1NR4A1NR4A2NR4A3
SCHEMBL1948692 0.82 PTPN1 (0.63) IDO1PTPN1NR4A1NR4A2NR4A3
SCHEMBL31401707 0.82 PTPN1 (0.63) IDO1PTPN1NR4A1NR4A2NR4A3
SCHEMBL3685318 0.82 PTPN1 (0.63) IDO1PTPN1NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0967674-B1 Solid polymer electrolytes HONDA MOTOR CO LTD (JP) 2006-03-22 EP disclosed
US-6124060-A A POLY-2,5-BENZIMIDAZOLE DOPED WITH AN ACID IN WHICH A HYDROGEN ATOM OF AN INORGANIC ACID IS REPLACED WITH A PHENYL GROUP; MADE BY A WRINKLE-RESISTANT SOLUTION BLEND METHOD; LOW WATER ABSORPTION; NO DOPANT LEAKAGE WHEN PRESSED; FUEL CELLS HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 2000-09-26 US disclosed
EP-0967674-A1 Solid polymer electrolytes HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 1999-12-29 EP disclosed
WO-1998037940-A1 METHOD OF REMOVING IMPURITIES FROM POLYMERS UTILIZING FACILITATED ION EXCHANGE HOECHST CELANESE CORPORATION (US) 1998-09-03 WO disclosed
US-5599639-A Acid-modified polybenzimidazole fuel cell elements HOECHST CELANESE CORPORATION (US) 1997-02-04 US disclosed
US-5264542-A Molding polybenzimidazole by immersion in a bath, sintering, heating and drying HOECHST CELANESE CORP. (US) 1993-11-23 US disclosed
WO-1991007455-A1 SULFOALKYLATION OF HYDROXYETHYLATED POLYBENZIMIDAZOLE POLYMERS HOECHST CELANESE CORPORATION (US) 1991-05-30 WO disclosed
US-4997892-A Sulfalkylation of hydroxyethylated polybenzimidazole polymers HOECHST CELANESE CORP. (US) 1991-03-05 US disclosed
US-4868249-A Cyanoethylation of hydroxyethylated polybenzimidazole polymers HOECHST CELANESE CORP. (US) 1989-09-19 US disclosed
US-4826502-A Sulfonation of hydroxyethylated polybenzimidazole fibers HOECHST CELANESE CORP. (US) 1989-05-02 US disclosed
US-4452972-A Production of high molecular weight polybenzimidazole with aryl phosphonic acid or aryl phosphinic acid catalyst CELANESE CORPORATION (US) 1984-06-05 US disclosed
US-4452967-A MELT POLYMERIZATION OF AROMATIC CARBOXY DIAMINE CELANESE CORPORATION (US) 1984-06-05 US disclosed
US-4448954-A Single stage production of improved high molecular weight polybenzimidazole with organosilicon halide catalyst. CELANESE CORPORATION (US) 1984-05-15 US disclosed
US-4448955-A Production of improved high molecular weight polybenzimidazole with tin containing catalyst CELANESE CORPORATION (US) 1984-05-15 US disclosed
EP-0103978-A1 Single stage production of improved high molecular weight polybenzimidazole CELANESE CORPORATION (US) 1984-03-28 EP disclosed
EP-0102171-A1 Production of improved high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-03-07 EP disclosed
US-4431796-A HEATING A MELT OF AROMATIC TETRAAMINE AND AROMATIC DICARBOXYLIC AC CELANESE CORPORATION (US) 1984-02-14 US disclosed
EP-0095348-A2 High molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1983-11-30 EP disclosed
US-4414383-A High molecular weight polybenzimidazole preparation with phosphorus containing polymerization catalyst CELANESE CORPORATION (US) 1983-11-08 US disclosed
US-4312976-A Single-stage melt polymerization process for the production of high molecular weight polybenzimidazole CELANESE CORPORATION (US) 1982-01-26 US disclosed