Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | CNR2 | P34972 | 2/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19540186 | 1.00 | PLD1 (0.66) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| SCHEMBL29389926 | 1.00 | PLD1 (0.66) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| SCHEMBL3154137 | 1.00 | PLD1 (0.66) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL10642748 | 0.98 | PLD1 (0.63) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL30864277 | 0.98 | PLD1 (0.63) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| Lithium SCHEMBL31260780 | 0.98 | PLD1 (0.63) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL27844704 | 0.98 | PLD1 (0.63) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| SCHEMBL29462629 | 0.98 | PLD1 (0.68) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| SCHEMBL230367 | 0.98 | PLD1 (0.68) | PLD1KDM4ECNR2GRIN2DGRIN3B | |
| SCHEMBL18228078 | 0.98 | PLD1 (0.68) | PLD1KDM4ECNR2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746966-A1 | 4-AMINO-2,6-BIS(PHENYLMETHYLENE)CYCLOHEXANONES AND THEIR USE | Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) | 2026-05-27 | — | — | EP | claimed |
| US-20250221977-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE AND USE THEREOF AS BET INHIBITOR | BENOBIO CO., LTD. (KR) | 2025-07-10 | — | — | US | claimed |
| WO-2025021236-A1 | 4-AMINO-2,6-BIS(PHENYLMETHYLENE)CYCLOHEXANONES AND THEIR USE | Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) | 2025-01-30 | — | — | WO | claimed |
| WO-2023195669-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE AND USE THEREOF AS BET INHIBITOR | 주식회사 베노바이오 | 2023-10-12 | — | — | WO | claimed |
| EP-4175633-A1 | THIENO[3,4-C]PYRAZOL-3-YL ACETAMIDES AS AUTOTAXIN INHIBITORS | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. (GR) | 2023-05-10 | — | — | EP | claimed |
| CN-115776907-A | MTORC1 modulators and uses thereof | 艾奥维安制药公司 | 2023-03-10 | — | — | CN | claimed |
| WO-2022003377-A1 | THIENO[3,4-C]PYRAZOL-3-YL ACETAMIDES AS AUTOTAXIN INHIBITORS | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2022-01-06 | — | — | WO | claimed |
| EP-2507239-B1 | AZACYCLIC SPIRO DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-03-13 | — | — | EP | claimed |
| CN-109161028-A | It is a kind of using Cucurbituril as the preparation method of the degradable type two-dimension polymer of structural unit | 四川大学 | 2019-01-08 | — | — | CN | claimed |
| EP-3077380-B1 | THIENOMETHYLPIPERAZINE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | SANOFI SA (FR) | 2018-07-25 | — | — | EP | claimed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | claimed |
| EP-1708718-A1 | TRIAZOLE DERIVATIVES WHICH INHIBIT VASOPRESSIN ANTAGONISTIC ACTIVITY | Pfizer Limited (GB) | 2006-10-11 | — | — | EP | claimed |
| WO-2005079808-A1 | TRIAZOLE DERIVATIVES WHICH INHIBIT VASOPRESSIN ANTAGONISTIC ACTIVITY | PFIZER LIMITED (GB) | 2005-09-01 | — | — | WO | claimed |
| EP-0783486-B1 | NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS | DU PONT PHARM CO (US) | 1999-10-13 | — | — | EP | claimed |
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| CN-1166167-A | Novel prostaglandin synthase inhibitors | DU PONT MERCK PHARMA (US) | 1997-11-26 | — | — | CN | claimed |
| EP-0783486-A1 | NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-16 | — | — | EP | claimed |
| US-5593994-A | ANTIINFLAMMATORY AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-01-14 | — | — | US | claimed |
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | claimed |
| WO-1996010012-A1 | NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-04-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250221977-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE AND USE THEREOF AS BET INHIBITOR | BET1, BRD4, BRD1 | PLD1 3997/4885KDM4E 229/4885CNR2 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.