Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 5/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825591 | 0.83 | GRN (0.56) | GRNSORT1SLC16A3NPSR1GAA | |
| SCHEMBL2224515 | 0.78 | SLC16A3 (0.49) | GRNSORT1SLC16A3NPSR1GAA | |
| SCHEMBL2225699 | 0.76 | SLC16A3 (0.50) | GRNSORT1SLC16A3NPSR1GAA | |
| SCHEMBL12050569 | 0.73 | GRN (0.64) | GRNSORT1NPSR1GAAMAPT | |
| SCHEMBL13990638 | 0.73 | GRN (0.64) | GRNSORT1NPSR1GAAMAPT | |
| SCHEMBL1010749 | 0.72 | GRN (0.62) | GRNSORT1NPSR1GAAMAPT | |
| SCHEMBL21919193 | 0.71 | GRN (0.61) | GRNSORT1NPSR1GAAMAPT | |
| SCHEMBL20866275 | 0.71 | MAPK14 (0.48) | GRNSORT1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL27890739 | 0.70 | PTGS1 (0.47) | GRNSORT1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL20933027 | 0.70 | GRN (0.63) | GRNSORT1NPSR1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1726580-A1 | AMINOPHENYLPROPANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2006-11-29 | — | — | EP | disclosed |