Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL6008898 | 1.00 | GRIK1 (0.32) | GRIK1FAAHEP300MEN1TP53 | |
| SCHEMBL15846660 | 0.95 | GRIK1 (0.34) | GRIK1FAAHEP300MEN1TP53 | |
| Trimethylammonium SCHEMBL148948 | 0.91 | — | — | |
| Trimethylammonium SCHEMBL148950 | 0.91 | — | — | |
| Trimethylammonium SCHEMBL28166567 | 0.87 | GRIK1 (0.39) | GRIK1FAAHEP300MEN1TP53 | |
| SCHEMBL28019047 | 0.85 | GRIK1 (0.31) | GRIK1 | |
| SCHEMBL5664730 | 0.85 | USP2 (0.31) | — | |
| Trimethylammonium SCHEMBL5454856 | 0.84 | — | — | |
| Water SCHEMBL28888820 | 0.84 | USP2 (0.31) | — | |
| SCHEMBL15845801 | 0.83 | GRIK1 (0.33) | GRIK1FAAHEP300MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071462-A1 | ARTICLES COMPRISING AN OIL CAPTURE POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 2018-04-19 | — | — | WO | claimed |
| US-20180100250-A1 | Articles Comprising an Oil Capture Polymer | THE PROCTER & GAMBLE COMPANY | 2018-04-12 | — | — | US | claimed |
| US-20060217285-A1 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | RHODIA CHIMIE (FR) | 2006-09-28 | — | — | US | claimed |