Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31401115 | 1.00 | KMT2A (0.39) | KMT2ANAMPTDPP8DPP9CTSK | |
| SCHEMBL2670527 | 0.90 | DPP8 (0.36) | KMT2ADPP8DPP9CTSKUTS2R | |
| SCHEMBL4748856 | 0.90 | DPP8 (0.36) | KMT2ADPP8DPP9CTSKUTS2R | |
| SCHEMBL4748025 | 0.87 | KMT2A (0.36) | KMT2ACTSKUTS2RCTSL | |
| SCHEMBL2670226 | 0.86 | UTS2R (0.36) | KMT2ACTSKUTS2RCTSSCTSL | |
| SCHEMBL2670542 | 0.86 | UTS2R (0.35) | KMT2ADPP8DPP9CTSKUTS2R | |
| SCHEMBL2670666 | 0.86 | UTS2R (0.36) | KMT2ACTSKUTS2RCTSSCTSL | |
| SCHEMBL2671260 | 0.86 | UTS2R (0.37) | KMT2ACTSKUTS2RCTSS | |
| SCHEMBL2671027 | 0.86 | UTS2R (0.37) | KMT2ACTSKUTS2RCTSS | |
| SCHEMBL4749646 | 0.85 | UTS2R (0.34) | KMT2ADPP8DPP9CTSKUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924213-B1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2006-06-28 | — | — | EP | disclosed |
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6191129-B1 | MICROBIOCIDES, BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0924213-A1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |