Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591666 | 0.90 | PRMT1 (0.31) | — | |
| SCHEMBL248362 | 0.82 | — | — | |
| SCHEMBL20301478 | 0.80 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL5464884 | 0.79 | — | — | |
| SCHEMBL290836 | 0.79 | — | — | |
| SCHEMBL15988037 | 0.78 | — | — | |
| SCHEMBL121847 | 0.78 | USP2 (0.32) | USP2 | |
| SCHEMBL2363468 | 0.78 | USP2 (0.32) | USP2 | |
| SCHEMBL929596 | 0.78 | — | — | |
| SCHEMBL375500 | 0.78 | USP2 (0.32) | USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496095-B1 | REFRIGERANT COMPOSITIONS AND USES THEREOF | TAKASAGO PERFUMERY CO LTD (JP) | 2006-12-20 | — | — | EP | disclosed |