Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | PARP1 | P09874 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | MPO | P05164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalamide SCHEMBL2427917 | 0.98 | MAPT (0.67) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| SCHEMBL20078583 | 0.91 | CYP3A4 (0.62) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| Benzoic Acid Hydrazide SCHEMBL83514 | 0.91 | CYP3A4 (0.62) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| Benzoic Acid Hydrazide SCHEMBL4515671 | 0.91 | CYP3A4 (0.62) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| Benzoic Acid Hydrazide SCHEMBL922906 | 0.89 | CYP3A4 (0.60) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| Benzoic Acid Hydrazide SCHEMBL6469726 | 0.89 | CYP3A4 (0.60) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| Benzoic Acid Hydrazide SCHEMBL490987 | 0.89 | CYP3A4 (0.60) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| Benzoic Acid Hydrazide SCHEMBL1128823 | 0.89 | CYP3A4 (0.60) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| SCHEMBL3780335 | 0.89 | CYP3A4 (0.67) | MAPTCYP3A4L3MBTL1BLMPMP22 | |
| Benzoic Acid Hydrazide SCHEMBL31491462 | 0.89 | CYP3A4 (0.60) | MAPTCYP3A4L3MBTL1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132441-B2 | Immunosuppressive effects of administration of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor | G.D. SEARLE & CO. (US) | 2006-11-07 | — | — | US | disclosed |