Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | G6PD | P11413 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | DAB2IP | Q5VWQ8 | 1/20 | 1.00 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.84 |
| ▸ | SHBG | P04278 | 2/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12027476 | 1.00 | ESR1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL13123058 | 1.00 | ESR1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL29565170 | 1.00 | ESR1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL15491309 | 1.00 | ESR1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL225052 | 1.00 | ESR1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL225053 | 1.00 | ESR1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL4206797 | 0.91 | CYP19A1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL2617357 | 0.91 | CYP19A1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL3868013 | 0.91 | CYP19A1 (1.00) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL5025553 | 0.91 | CYP19A1 (1.00) | ESR1ESR2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060083778-A1 | Controlled release compositions of estradiol metabolites | PR PHARMACEUTICALS INC. | 2006-04-20 | — | — | US | disclosed |