Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008923 | 0.94 | EGFR (0.69) | EGFR | |
| SCHEMBL5398416 | 0.94 | EGFR (0.71) | EGFR | |
| SCHEMBL4445113 | 0.91 | EGFR (0.75) | EGFR | |
| Hydrochloric Acid SCHEMBL4448497 | 0.91 | EGFR (0.74) | EGFR | |
| SCHEMBL4448863 | 0.90 | EGFR (0.85) | EGFR | |
| Hydrochloric Acid SCHEMBL4445060 | 0.89 | EGFR (0.84) | EGFR | |
| SCHEMBL6009634 | 0.87 | EGFR (0.72) | EGFR | |
| SCHEMBL6009151 | 0.87 | EGFR (0.71) | EGFR | |
| SCHEMBL4444419 | 0.85 | EGFR (0.69) | EGFR | |
| SCHEMBL4453319 | 0.85 | EGFR (0.75) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713781-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005075439-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |