Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6009610 | 0.89 | — | — | |
| SCHEMBL4065629 | 0.84 | NPC1 (0.33) | NPC1RAB9A | |
| Iodide SCHEMBL6010399 | 0.80 | — | — | |
| Iodide SCHEMBL5538012 | 0.78 | — | — | |
| SCHEMBL5193951 | 0.78 | — | — | |
| Iodide SCHEMBL379644 | 0.78 | — | — | |
| SCHEMBL623161 | 0.75 | — | — | |
| Iodide SCHEMBL1226177 | 0.74 | HTT (0.35) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL17004512 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL4231892 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006126861-A1 | SOLID-STATE ELECTROLYTE COMPOSITION CONTAINING LIQUID CRYSTAL MATERIALS AND DYE-SENSITIZED SOLAR CELLS USING THEREOF | BUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2006-11-30 | — | — | WO | disclosed |