Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.57 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539511 | 0.93 | KCNH2 (0.48) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL5537382 | 0.92 | KCNH2 (0.47) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL5542184 | 0.92 | KCNH2 (0.48) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL6010637 | 0.91 | KCNH2 (0.51) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL5542291 | 0.91 | KCNH2 (0.46) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| Hydrochloric Acid SCHEMBL5541526 | 0.91 | KCNH2 (0.47) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL5543792 | 0.90 | KCNH2 (0.46) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL5537724 | 0.90 | KCNH2 (0.46) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL14562880 | 0.90 | KCNH2 (0.47) | KCNH2CACNA1CSCN5APTGS1SLC6A2 | |
| SCHEMBL6010965 | 0.90 | KCNH2 (0.64) | KCNH2CACNA1CSCN5APTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | KCNH2 3503/4885CACNA1C 3762/4885SCN5A 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.