Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539213 | 0.91 | KCNH2 (0.65) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL5539219 | 0.91 | KCNH2 (0.65) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL6010803 | 0.90 | KCNH2 (0.63) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL6010760 | 0.90 | PTGS1 (0.63) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL3466162 | 0.89 | KCNH2 (0.64) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL16624970 | 0.88 | KCNH2 (0.60) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL6010775 | 0.87 | KCNH2 (0.71) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL5539475 | 0.84 | KCNH2 (0.75) | KCNH2KMT2ASMN1; SMN2PTGS1SLC6A2 | |
| SCHEMBL6010805 | 0.84 | KCNH2 (0.56) | KCNH2KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL5539481 | 0.84 | KCNH2 (0.75) | KCNH2KMT2ASMN1; SMN2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | KCNH2 3503/4885KMT2A 4267/4885SMN1; SMN2 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.