SCHEMBL6012363

SCHEMBL6012363

C1CNCCC2(C1)CNCCN2

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451665 0.91 HIF1A (0.33)
SCHEMBL16877906 0.91 HIF1A (0.33)
SCHEMBL31085590 0.88
SCHEMBL473641 0.88
Hydrochloric Acid SCHEMBL4827298 0.88 HIF1A (0.32)
SCHEMBL22924480 0.88
SCHEMBL16878294 0.88 CXCR4 (0.33) CXCR4SMN1; SMN2
Hydrochloric Acid SCHEMBL31450253 0.86
SCHEMBL16877717 0.86 CXCR4 (0.38) CXCR4SMN1; SMN2
SCHEMBL5429657 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7119091-B2 Triazaspiro[5.5]undecane derivatives and pharmaceutical compositions comprising thereof, as an active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2006-10-10 US disclosed