Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.76 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189699 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL27088024 | 0.88 | SOS1 (0.79) | SOS1SOS2TSHRSLC6A2SLC6A4 | |
| SCHEMBL14161267 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1190602 | 0.88 | SOS1 (0.79) | SOS1SOS2TSHRSLC6A2SLC6A4 | |
| SCHEMBL17609001 | 0.87 | SOS1 (0.64) | SOS1SOS2TSHRSLC6A2SLC6A4 | |
| SCHEMBL14826665 | 0.86 | SOS1 (0.91) | SOS1SOS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14826667 | 0.86 | SOS1 (1.00) | SOS1SOS2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL31076497 | 0.86 | SOS1 (0.63) | SOS1SOS2TSHRSLC6A2SLC6A4 | |
| SCHEMBL24722834 | 0.84 | SOS1 (0.96) | SOS1SOS2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19320636 | 0.84 | SOS1 (0.73) | SOS1SOS2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119091-B2 | Triazaspiro[5.5]undecane derivatives and pharmaceutical compositions comprising thereof, as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |